Melatonin in Humans – The Right Dosage

Melatonin Dosage for Adults

There isn’t any fixed suggested dose for melatonin in adults. People give different responses to its effects. Lower doses emerge to work enhanced in people who are particularly sensitive. Higher doses could cause anxiety and tetchiness.

The best recommendation is to begin with very low doses of melatonin. Keep the dose close to the quantity that our bodies normally make (< 0.3 mg per day). You ought to only use the lowest amount likely to achieve the preferred effect. Your doctor can help you to decide the most suitable dose for your condition.

Here is some recommended dose for melatonin for adults.

Insomnia: 1 to 3 mg 1 hour prior to bedtime is usually useful, for patients with sleeping problems, although doses as low as 0.1 -0.3 mg may get better sleep for some people. If 3 mg per night does not work after 3 days, try 5 – 6 mg 1 hour prior to bedtime. You need to work with your doctor to find the harmless and most effective dose for you. The right dose for you be supposed to produce restful sleep with no daytime touchiness or fatigue.

Melatonin Dosage

Jet lag: 0.5 – 5 mg of melatonin 1 hour before bedtime at final purpose has been used in several studies. Another approach that has been used is 1 – 5 mg 1 hour prior to bedtime for 2 days before leaving and for 2 – 3 days upon arrival at final destination.

Melatonin Dosage for Kids

The melatonin hormone supports the body maintain its daily rhythm, the interior clock that controls a person’s sleeping cycle. Night arouses ooze of the hormone. Despite children having the highest levels of hours of darkness melatonin, some children do not yield enough of the hormone that might be why they have sleep problems.

Talk to your child’s doctor previously giving him / her melatonin. Though currently there is no suggested melatonin dosage for kids, several paediatricians’ advice doses less than 0.3 mg per day, preferably in liquid form. This is nearby to the amount of melatonin the body creates naturally. There is anxiety that higher doses 1 mg to 5 mg might cause seizures in children, specifically those with serious neural disorders.

Evidence advocates that it is not active in treating most sleep disorders with immediate use. Studies on children have been limited and there is no material on the long-term effects of the supplement and the melatonin dosage. The U.S. Food and Drug Administration have not approved the use of melatonin. Talk to your child’s paediatrician first to rule out potential medical causes for her insomnia.

Melatonin Research in Kids

Melatonin has been investigated under several research studies, however there are very few studies that are based on children. Some studies that are conducted on a few children, yielded that it is a safe way of promoting sleep in kids. Most of the studies are based on kids who suffers from neurological disorders. Autistic children and those with ADHD have difficulty falling asleep and, in such conditions, melatonin can be very helpful. Melatonin works because the production of this hormone is less and sometimes totally absenting in kids that suffer ADHD, autistic and visually impaired. Most doctors and sleep specialists do not prescribe melatonin for healthy children because there has been little research about the long-term side effects of melatonin on healthy children.

Using melatonin for children appears to be safe if the frequency of use for melatonin is kept to no more than twice a week and the dosage is 0.5 mg or less. Additional research with melatonin and its effect on children will tell us if more frequent use and higher dosage is safe and effective.  Children will also experience the same melatonin side effects commonly experienced by adults taking melatonin.

Parents who are considering using melatonin on their kids, should first discuss this matter with the child’s paediatrician. The paediatrician can rule out other medical conditions that cause insomnia, like breathing difficulties or behavioural conditions like attention deficit disorder. Before giving your child melatonin, you should try changing the behaviour of the child so that he/she can sleep easily. You can try limiting television before bedtime or cut down caffeine.

Reference: Melatonin improves health status and sleep in children with idiopathic chronic sleep-onset insomnia: a randomized placebo-controlled trial.  J Am Accad Child Adolescent Psychiatry. 2003.

– A randomized, double-blind, placebo-controlled trial was conducted in a Dutch sleep center, involving 62 children, 6 to 12 years of age, who suffered more than 1 year from idiopathic chronic sleep-onset insomnia. Patients received either 5 mg melatonin or placebo at 7 pm. Melatonin treatment significantly advanced sleep onset by 57 minutes, sleep offset by 9 minutes, and melatonin onset by 82 minutes, and decreased sleep latency by 17 minutes.

Melatonin References:

Claustrat, B., Brun, J., David, M., Sassolas, G., & Chazot, G. (1992).

Melatonin and Jet Lag: Confirmatory Result Using a Simplified Protocol. Biological Psychiatry, 32, 705-711.

Garfinkel, D., Laudon, M., Nof, D., & Zisapel, N. (1995). Improvement of sleep quality in elderly people by controlled-release melatonin. The Lancet, 346, 541-543.

Jan, J. (1994). The Treatment of Sleep Disorders With Melatonin. Developmental Medicine and Child Neurology, 36, 97-107.

Lino, A., Silvy, S., Condorelli, L., & Rusconi, A. (1993). Melatonin and Jet Lag: Treatment Schedule. Biological Psychiatry, 34, 587.

Zhdanova, I. (1995). Sleep – inducing effects of low doses of melatonin ingested in the evening. Clinical Pharmacology & Therapeutics, 57, 552-558.

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